Bacterial infection – Communicable Diseases Research

Determinants of poor clinical outcome in patients with influenza pneumonia: A systematic review and meta-analysis

Meta-Analysis

Published on 2023-06-012023-06-24
Journal: International Journal of Infectious Diseases
[Category] 신종인플루엔자,

Evaluation of Procalcitonin’s Utility to Predict Concomitant Bacterial Pneumonia in Critically Ill COVID-19 Patients

Article

Published on 2022-11-012022-11-15
Journal: Journal of Intensive Care Medicine
[Category] 바이오마커,

[키워드] Antibiotic therapy AUC Bacteremia Bacterial Bacterial infection bacterial pneumonia baseline characteristics Concomitant conducted COVID-19 creatinine Critical Critical illness Critically ill patient Culture defined determine diagnosing diagnostic ENhance evaluate group hospitalized patients ICU ICU patient identify Ill in-hospital mortality intensive care intensive care unit Mortality multivariable multivariable model no difference no significant difference offer outcome Patient PCT Pneumonia positive predict Predictive procalcitonin procalcitonin. receiver operating characteristics Regression model retrospective cohort study ROC SARS-CoV-2 secondary bacterial pneumonia serum creatinine Severe COVID-19 pneumonia Severity of disease specificity threshold utility variable vital signs was used while with COVID-19
[DOI] 10.1177/08850666221108636 PMC 바로가기

Increased Detection of Carbapenemase-Producing Enterobacterales Bacteria in Latin America and the Caribbean during the COVID-19 Pandemic

Article

Published on 2022-11-012022-11-16
Journal: Emerging Infectious Diseases
[Category] 치료기술,

[키워드] acute respiratory syndrome antibiotic use antimicrobial resistance Bacteria Bacterial infection Carbapenemase-producing Enterobacterales change characterized clinical setting coronavirus coronavirus disease Corso A country COVID-19 COVID-19 cases COVID-19 pandemic detection enteric infections et al. Increased detection of carbapenemase-producing Enterobacterales bacteria in Latin America and the Caribbean during the COVID-19 pandemic. Emerg Infect Dis. 2022 Nov [date cited]. https://doi.o food safety healthcare help increase Increased Infection prevention isolates Latin Latin America limitation Pasterán F Pillonetto M Prevalence Prevent reported Research respiratory infections resulting SARS SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 Shal J Sosa A Suggested citation for this article: Romero Thomas G Surveillance the Caribbean Thoma Transmission viruses zoonoses zoonoses.
[DOI] 10.3201/eid2811.220415 PMC 바로가기

Amikacin-loaded niosome nanoparticles improve amikacin activity against antibiotic-resistant Klebsiella pneumoniae strains

Article

Published on 2022-10-032022-11-16
Journal: World journal of microbiology & biotechnology
[Category] COVID19(2023년), SARS, 유전자 메커니즘,

Artificial Neural Network-Based Study Predicts GS-441524 as a Potential Inhibitor of SARS-CoV-2 Activator Protein Furin: a Polypharmacology Approach

Article

Published on 2022-10-012022-11-15
Journal: Applied biochemistry and biotechnology
[Category] COVID19(2023년), SARS, 신약개발, 치료제,

Complementary Sets of Autoantibodies Induced by SARS-CoV-2, Adenovirus and Bacterial Antigens Cross-React with Human Blood Protein Antigens in COVID-19 Coagulopathies

Article

Published on 2022-09-292022-11-15
Journal: International Journal of Molecular Sciences
[Category] SARS, 진단,

[키워드] Adenovirus antibody antigenic antigenic complementarity antigens autoantibody Autoimmune Autoimmunity Bacteria Bacterial Bacterial infection binding constant Blood bystander bystander infection cardiolipin Clostridia coagulation factor Coagulopathies Coagulopathy Combination COVID-19 cross-reactive develop E. coli Escherichia coli Factor factor IX factor VIII function glycoprotein Human induced infections Interaction investigated involved Klebsiella pneumoniae moderate-to-severe COVID-19 MOST mRNA mRNA vaccine Mycobacterium tuberculosis Patient PF4 Platelet platelet factor 4 polyclonal antibody Protein Proteins recognize Research SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 proteins serum albumin similarity Staphylococcus Streptococcus stroke tested thrombocytopenia thrombosis thrombotic vaccine-induced thrombotic thrombocytopenia virus von Willebrand factor von Willebrand factor.
[DOI] 10.3390/ijms231911500 PMC 바로가기

IFI44 is an immune evasion biomarker for SARS-CoV-2 and Staphylococcus aureus infection in patients with RA

Article

Published on 2022-09-152022-11-15
Journal: Frontiers in Immunology
[Category] SARS, 바이오마커, 유전자 메커니즘,

[키워드] 1,25-dihydroxy vitamin D3 activated acute respiratory syndrome analyses Analysis applied autoimmune conditions Bacteremia Bacterial Bacterial infection Bacterial infections Bioinformatics analysis Biomarker caused Cell cell membrane CIBERSORT conducted coronavirus COVID-19 Cytoscape database dataset datasets DEGs dendritic cell dendritic cells dendritic cells. differentially expressed differentially expressed gene disease DNA drug target Effectiveness examined expression FIVE functional enrichment Functional enrichment analysis GBP1 gene network GeneMANIA Genes global pandemic HERC5 humans identify Ifi44 IFI44L IFIT3 IFIT5 IFN signaling IFN signaling pathway IFN-α/β Immune cell infiltration immune cells Immune escape immune evasion immune system Immunological response Infection infections infiltration Intersection ISG15 KEGG mechanism miRNA molecular mechanism molecular target NLR OAS1 oxidative phosphorylation pathogenic bacteria pathway Patient platform positive correlation PPI network prevalent proliferation promote regulate Regulation Rheumatoid rheumatoid arthritis risk factor ROC curves RSAD2 Rtp4 SARS-CoV-2 SARS-COV-2 infection severe coronavirus disease signaling pathway Staphylococcus Staphylococcus aureus target the SARS-CoV-2 therapeutic viral infection viral replication virus were used YY1
[DOI] 10.3389/fimmu.2022.1013322 PMC 바로가기

Plasma microRNA and metabolic changes associated with pediatric acute respiratory distress syndrome: a prospective cohort study

Research

Published on 2022-08-262022-10-05
Journal: Scientific Reports
[Category] 바이오마커,

[키워드] acute respiratory distress ARDS Bacterial infection Biomarker Biomarkers both groups change circulating circulation Clinical characteristics conducted control patient correlated Critically ill defined differential expression differentially expressed distress evaluate heterogeneous identify intensive care patients metabolite metabolomics microRNA MicroRNAs miRNA miRNA expression morbidity and mortality non-coding RNA pathophysiological Patient pediatric Pediatric patient Pediatric patients pilot study prognostic biomarker progression prospective cohort study provide Random forest random forest classification responsible risk selected single-center sub-cohort subset syndrome therapeutic intervention
[DOI] 10.1038/s41598-022-15476-0 [Article Type] Research

Temporal dynamics of oropharyngeal microbiome among SARS-CoV-2 patients reveals continued dysbiosis even after Viral Clearance

Research

Published on 2022-08-242022-10-05
Journal: NPJ Biofilms and Microbiomes
[Category] SARS, 유전자 메커니즘,

[키워드] acute respiratory syndrome administration Antibiotics Azithromycin Bacteria Bacterial infection Bacterial sepsis bacterial species Chryseobacterium clinical Clinical diagnosis clinically commensal bacteria compensated Complication complications Coronavirus-2 elevated feature Firmicute global public health healthy controls Human include indicate individuals Infection Influenza Klebsiella lung Lung infection microbial Microbiome morbidity and mortality observation oral organism Oropharyngeal oropharynx outbreak pandemic persist Pneumonia present proportion Proteobacteria reduced respiratory virus response reveal SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 patient SARS-CoV-2 positive individual secondary bacterial infection Sepsis shown stability Temporal the patient viral clearance
[DOI] 10.1038/s41522-022-00330-y [Article Type] Research

JAK inhibition as a new treatment strategy for patients with COVID-19

Review article

Published on 2022-08-012022-10-05
Journal: Biochemical pharmacology
[Category] COVID19(2023년), SARS, 바이오마커, 신약개발, 임상, 치료법,

[키워드] AAK1 ACE-2 acute respiratory syndrome adverse outcomes angiotensin-converting enzyme 2 Bacterial infection blockers caused clinical trial clinical trials Combination coronavirus coronavirus disease Corticosteroids Course COVID-19 Critical cytokine Cytokine storm Cytokines Cytokines storm develop discharge Disease progression dysregulated effective Epidemic Future GAK greater herpes zoster Host ICU admission IL-2 IL-6 IL-6 receptor immune improve clinical outcome increased risk Infection Inflammation inhibit inhibiting involved Jak JAK inhibition JAK inhibitor Jak-STAT JAK/STAT JAK/STAT signaling janus medication medications Mortality MOST new treatment strategy offer pathway Patient patients with COVID-19 pro-inflammatory cytokine raised regulate released SARS-CoV-2 severe pneumonia significantly Spread Thromboembolic events TNF-α Transcription transmembrane protein Treatment upregulated viral endocytosis virus virus infection WHO guideline
[DOI] 10.1016/j.bcp.2022.115162 [Article Type] Review article